Lancashire and South Cumbria
Formulary
 
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1 Gastro-intestinal system
01-05-03 JAK inhibitors

Tofacitinib
Formulary

Tablets 5mg, 10mg, MR tablets 11mg

Link  NICE TA547: Tofacitinib for moderately to severely active ulcerative colitis
Link  MHRA: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
Link  MHRA: Tofacitinib (Xeljanz▼): new measures to minimise risk of major adverse cardiovascular events and malignancies
Link  MHRA: Tofacitinib (Xeljanz▼): new measures to minimise risk of venous thromboembolism and of serious and fatal infections

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Upadacitinib  Rinvoq®
Formulary

Prolonged release tablets 15mg, 30mg, 45mg

Link  NICE TA905: Upadacitinib for previously treated moderately to severely active Crohn’s disease
Link  MHRA: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
Link  NICE TA856: Upadacitinib for treating moderately to severely active ulcerative colitis

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Filgotinib
Formulary

Tablet 100mg, 200mg

Moderately to severely active ulcerative colitis

Link  NICE TA792: Filgotinib for treating moderately to severely active ulcerative colitis

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