Lancashire and South Cumbria
Formulary
 
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2 Cardiovascular system
02-09 Antiplatelet drugs

Aspirin tablets (antiplatelet)
Formulary

Dispersible tablets 75mg, 300mg


The use of enteric coated aspirin 75mg is not recommended


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Clopidogrel
Formulary
Tablets 75mg
Link  MHRA: Clopidogrel and proton pump inhibitors: interaction—updated advice
Link  MHRA: Clopidogrel: risk of acquired haemophilia
Link  NICE NG185: Acute coronary syndromes
Link  NICE TA210- Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events

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Dipyridamole
Formulary

Tablets 25mg, 100mg
M/R capsules 200mg


Link  NICE NG128: Stroke and transient ischaemic attack in over 16s: diagnosis and initial management
Link  NICE TA210- Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events

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Prasugrel
Formulary

Tablets 5mg, 10mg


Link  LSCMMG: Prasugrel
Link  MHRA: Prasugrel (Efient▼): rare but serious hypersensitivity reactions
Link  MHRA: Prasugrel (Efient): increased risk of bleeding
Link  NICE TA317- Prasugrel with percutaneous coronary intervention for treating acute coronary syndromes

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Ticagrelor
Formulary

Tablets 60mg, 90mg

Link  NICE NG185: Acute coronary syndromes
Link  NICE TA236 - Ticagrelor for the treatment of acute coronary syndromes
Link  NICE TA420 - Ticagrelor for preventing atherothrombotic events after myocardial infarction

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Tirofiban
Formulary
Used in some Trusts for emergency use in cath lab
Specialist use only, follow local protocol

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