Lancashire and South Cumbria
Formulary
 
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4 Central nervous system
04-01-01 Non-benzodiazepine hypnotics and sedatives

Avoid prescribing hypnotics. Hypnotics licensed for short term use only - If needed, use for 1-3 days only. Do not supply on discharge from hospital.
On specialist advice only, some patients with long term psychiatric problems may require long term use.

 


Zopiclone
Formulary

Tablets 3.75mg, 7.5mg

First line short-term hypnotic.


If commenced in hospital, not to be continued at discharge.
May have CD status in some hospital Trusts, refer to local policy.


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Daridorexant
Formulary

Tablets 25mg, 50mg

Treatment of long-term insomnia

Link  NICE TA922: Daridorexant for treating long-term insomnia

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Melatonin
Formulary

Children with learning disabilities

Children with ADHD

Children and adolescents with Autism Spectrum Disorder (ASD) and / or Smith-Magenis syndrome

Cerebral palsy

Children with complex neurodevelopmental disorders that the specialist considers eligible

 

Initiation of melatonin must be by a specialist in the indication being prescribed for and have a clear plan for review.

Prescribing and review of melatonin in children must follow the principles outlined in the Melatonin Pathway (Children)

Link  LSCMMG: Melatonin Pathway (Children)

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Melatonin
Formulary

For the Treatment of Rapid Eye Movement (REM) Sleep Behaviour Disorder (RBD) in Parkinson’s Disease and Lewy Body Dementia

Adults with learning disabilities

Sleep disturbance in adults with ADHD

Sleep disorders in the blind

Adults with complex neurodevelopmental disorders that the specialist considers eligible

 

Initiation of melatonin must be by a specialist in the indication being prescribed for and have a clear plan for review.

Prescribing and review of melatonin in adults must follow the principles outlined in the Melatonin Pathway (adults) **Under development**.

Melatonin is suitable for prescribing for the treatment of REM RBD in PD and LBD when clonazepam is not considered to be appropriate.

Link  LSCMMG: Melatonin

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Melatonin
Formulary

Primary insomnia in those over 55

Sleep problems in patients with dementia associated with Alzheimer’s

Colonis liquid 1mg/ml and 3mg tablets for all indications, including insomnia and jet lag

Link  LSCMMG: Melatonin

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Zolpidem
Formulary

Tablets 5mg, 10mg

If commenced in hospital, not to be continued at discharge.

Link  MHRA: Zolpidem: risk of drowsiness and reduced driving ability

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