Lancashire and South Cumbria
Formulary
 
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4 Central nervous system
04-09-01 Catachol-O-methyltransferase inhibitors

Entacapone Comtess®
Formulary

Tablets 200mg

Adjunct to co-beneldopa or co-careldopa in Parkinson's disease.


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Opicapone Ongentys®
Formulary

Capsules 50mg

Adjunctive therapy in adults with end-of-dose motor fluctuations who cannot be stabilised on preparations of levodopa/DOPA decarboxylase inhibitors.


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Tolcapone Tasmar®
Formulary

Tablets 100mg

Tolcapone as an adjunct to co-beneldopa or co-careldopa in Parkinson's disease with 'end-of-dose' motor fluctuations if another inhibitor of peripheral catechol-O-methyltransferase is inappropriate.

Third Line.


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