Lancashire and South Cumbria
Formulary
 
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4 Central nervous system

This chapter of the formulary is under continual development, please let the team know if you have any comments about the contents: mlcsu.lscformulary@nhs.net

For more information about the formulary development process, please see: https://www.lancsmmg.nhs.uk/lancashire-and-south-cumbria-icb-formulary-development/

04-06 5HT3 antagonists

Ondansetron
Formulary

Tablets 8mg
Liquid 4mg/5mL
Injection 4mg/2mL, 8mg/4mL

MHRA warning – risk of prolongation of the QT interval. Maximum single dose of ondansetron injection for the management of chemotherapy-induced nausea and vomiting in adults is 16mg.

Link  MHRA: Ondansetron: small increased risk of oral clefts following use in the first 12 weeks of pregnancy
Link  NICE: Management of vomiting in children and young people with gastroenteritis: ondansetron

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