Lancashire and South Cumbria
Formulary
 
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4 Central nervous system

This chapter of the formulary is under continual development, please let the team know if you have any comments about the contents: mlcsu.lscformulary@nhs.net. 

For more information about the formulary development process, please see: https://www.lancsmmg.nhs.uk/lancashire-and-south-cumbria-icb-formulary-development/

04-08-01 Other Drugs

Cenobamate  Ontozry®
Formulary

Tablets 12.5mg*, 25mg* (*initiation pack) 50mg, 100mg, 150mg, 200mg

Cenobamate is recommended as an option for treating focal onset seizures with or without secondary generalised seizures in adults with drug-resistant epilepsy that has not been adequately controlled with at least 2 antiseizure medicines. It is recommended only if:

  • it is used as an add-on treatment, after at least 1 other add-on treatment has not controlled seizures, and

  • treatment is started in a tertiary epilepsy service.
Link  NICE TA753: Cenobamate for treating focal onset seizures in epilepsy

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Perampanel Fycompa®
Formulary

Tablets f/c 2mg,4mg, 6mg, 8mg, 10mg, 12mg

Suspension 500micrograms/1mL

 

Category 2 - Doctors should use clinical judgement when deciding whether to switch between different manufacturer's products
Link  NICE NG217: Epilepsies in children, young people and adults

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Stiripentol Diacomit®
Formulary

Capsules 250mg, 500mg

Powder for oral suspension in sachet 250mg, 500mg

RED RAG (for all ages) for continuation of treatment of patients who have previously received the drug during childhood under the NHSE standard contract for paediatric neurosciences - neurology. Not to be newly initiated in adults

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