Lancashire and South Cumbria
Formulary
 
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5 Infections

 

Prescribers must follow the relevant local and national guidance when treating an infection. Some anti-infectives require approval from the local Trust microbiology team for use, consult local guidance for further information.

Not all anti-infectives listed in this chapter will be available in all localities; availability will be guided by local need and resistance patterns.

05-01-04 Aminoglycosides

Amikacin
Formulary

Injection 500mg/2mL

Restricted Item  For neutropenia in children undergoing chemotherapy - Manchester protocol

Link  MHRA: Liposomal and lipid-complex formulations: name change to reduce medication errors

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Gentamicin
Formulary

Injection 20mg/2mL (paediatric), 80mg/2mL

Gentamicin for nebulisation
Gentamicin injection (nebulised) is recommended by the British Thoracic Society as a second line option for non-cystic fibrosis bronchiectasis in adults (unlicensed use). Caution should be taken when selecting the gentamicin product, it should be alcohol-free. Treatment should be initiated by a respiratory consultant.
NB. In the Pennine region this treatment is RAG rated Amber 0 .


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Neomycin Sulphate
Formulary

Tablets 500mg

Only available as unlicensed import.
On advice of Microbiology only.


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Tobramycin
Formulary

Injection 80mg/2mL, 240mg/6mL
Nebuliser solution 300mg/5mL
Inhalation powder capsules with device 28mg

On advice of Microbiology only.
Nebuliser solution restricted for use in cystic fibrosis patients only.

Link  NICE TA276: Colistimethate sodium and tobramycin dry powders for inhalation for treating pseudomonas lung infection in cystic fibrosis

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