Prescribers must follow the relevant local and national guidance when treating an infection. Some anti-infectives require approval from the local Trust microbiology team for use, consult local guidance for further information.Not all anti-infectives listed in this chapter will be available in all localities; availability will be guided by local need and resistance patterns. |
Bedaquiline |
Formulary
|
Tablets 100mg On advice of Microbiology or a respiratory consultant only. |
NHSE: Clinical commissioning policy for resistant TB |
|
Delamanid |
Formulary
|
Tablets 50mg On advice of Microbiology or a respiratory consultant only. |
NHSE: Clinical commissioning policy statement (2317): treatment for defined patients with rifampicin resistant (RR) tuberculosis (TB), multidrug-resistant (MDR) TB, pre-extensively drug-resistant (pre-XDR) TB and extensively drug-resistant (XDR-TB) includ |
|
Ethambutol |
Formulary
|
Tablets 100mg, 400mg |
|
Isoniazid |
Formulary
|
Tablets 100mg Use Rifater® where possible. On advice of Microbiology or a respiratory consultant only. |
|
Pretomanid |
Formulary
|
On advice of Microbiology or a respiratory consultant only. |
NHSE: Clinical commissioning policy for resistant TB |
|
Pyrazinamide |
Formulary
|
Tablets 500mg Use Rifater® where possible On advice of Microbiology or a respiratory consultant only. |
|
Rifampicin |
Formulary
|
Capsules 150mg, 300mg On advice of Microbiology or a respiratory consultant only. May be prescribed by GP upon consultant microbiologist advice. |
|
Rifampicin |
Formulary
|
Intravenous infusion 600mg On advice of Microbiology or a respiratory consultant only. |
|
Rifampicin and Isoniazid and Pyrazinamide Rifater® |
Formulary
|
Tablets rifampicin 120mg, isoniazid 50mg, pyrazinamide 300mg On advice of Microbiology or a respiratory consultant only. |
|