Lancashire and South Cumbria
Formulary
Formulary
5 Infections
Prescribers must follow the relevant local and national guidance when treating an infection. Some anti-infectives require approval from the local Trust microbiology team for use, consult local guidance for further information.Not all anti-infectives listed in this chapter will be available in all localities; availability will be guided by local need and resistance patterns. |
05-03-04 Influenza
| Oseltamivir |
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Formulary
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Capsules 30mg, 45mg, 75mg Influenza treatment & prophylaxis (NICE TA158 & 168). Only if national surveillance schemes indicate that influenza virus A or B is circulating. Public Health England advises that oseltamivir oral suspension should be reserved for children under the age of 1 year. Children over 1 year of age, adults with swallowing difficulties, and those receiving nasogastric oseltamivir, should use capsules which can be opened and mixed into an appropriate sugary liquid. Tamiflu® is not prescribable in NHS primary care except for the treatment and prophylaxis of influenza as indicated in the NICE guidance; endorse prescription ‘SLS’. |
 NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza NICE TA168: Amantadine, oseltamivir and zanamivir for the treatment of influenza |
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| Zanamivir Relenza® |
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Formulary
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Dry powder for inhalation 5mg/blister Relenza® is not prescribable in NHS primary care except for the treatment and prophylaxis of influenza as indicated in the NICE guidance; endorse prescription ‘SLS’. |
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LSCMMG: Zanamivir NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza NICE TA168: Amantadine, oseltamivir and zanamivir for the treatment of influenza |
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| Amantadine |
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Formulary
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Influenza treatment & prophylaxis (NICE TA158 & 168). |
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NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza NICE TA168: Amantadine, oseltamivir and zanamivir for the treatment of influenza |
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Links
- Remdesivir for patients hospitalised with COVID-19 (adults and children aged 12 years and older) - Supply Disruption
Blackpool Teaching Hospitals: Antimicrobial Formulary- British Association for Sexual Health and HIV
- Dapsone for the treatment of Dermatitis Herpetiformis, other dermatoses and Vasculitis shared care guideline
- East Lancashire Primary Care: Antimicrobial guide primary care
- East Lancashire Secondary Care: Antimicrobial guide secondary care
- Greater Preston, Chorley and South Ribble/LSCFT/Morecambe Bay Primary Care: NICE Summary of antimicrobial prescribing guidance - managing common infections
- HPA guidance on use of antivirals (includes ordering information for IV zanamivir)
- Lancashire Teaching Hospitals Secondary Care: Tap on the bugs app (App store)
- Lancashire Teaching Hospitals Secondary Care: Tap on the bugs app (Google)
- LSCMMG Recurrent UTI Prophylactic Antibiotic Pathway
- LSCMMG: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab
- LSCMMG: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab
- LSCMMG: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab
- LSCMMG: Zanamivir
- MHRA: COVID-19 antivirals: reporting to the UK COVID-19 Antivirals Pregnancy Registry
- MHRA: COVID-19 antivirals: reporting to the UK COVID-19 Antivirals Pregnancy Registry
- MHRA: Nirmatrelvir, ritonavir (Paxlovid▼): be alert to the risk of drug interactions with ritonavir
- MHRA: Tocilizumab (RoActemra): rare risk of serious liver injury including cases requiring transplantation
- NHS England Interim Clinical Commissioning Policy: Remdesivir for patients hospitalised with COVID-19 (adults and children 12 years and older)
- NICE CG165: Hepatitis B (chronic): diagnosis and management
- NICE CG97: Lower urinary tract symptoms in men: management
- NICE ES27: COVID 19 rapid evidence summary: Remdesivir for treating hospitalised patients with suspected or confirmed COVID-19
- NICE NG109: Urinary tract infection (lower): antimicrobial prescribing
- NICE NG112: Urinary tract infection (recurrent): antimicrobial prescribing
- NICE NG113: Urinary tract infection (catheter-associated): antimicrobial prescribing
- NICE NG120: Cough (acute): antimicrobial prescribing
- NICE NG125: Surgical site infections: prevention and treatment
- NICE NG19: Diabetic foot problems: prevention and management
- NICE NG191 COVID-19 rapid guideline: managing COVID-19
- NICE NG191: COVID-19 rapid guideline: managing COVID-19
- NICE NG191: COVID-19 rapid guideline: managing COVID-19
- NICE NG191: COVID-19 rapid guideline: managing COVID-19
- NICE NG240: Meningitis (bacterial) and meningococcal disease: recognition, diagnosis and management
- NICE NG51: Sepsis: recognition, diagnosis and early management
- NICE NG78: Cystic fibrosis: diagnosis and management
- NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
- NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
- NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
- NICE TA168: Amantadine, oseltamivir and zanamivir for the treatment of influenza
- NICE TA168: Amantadine, oseltamivir and zanamivir for the treatment of influenza
- NICE TA168: Amantadine, oseltamivir and zanamivir for the treatment of influenza
- NICE TA732: Baloxavir marboxil for treating acute uncomplicated influenza (terminated appraisal)
- NICE TA878 Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA878 Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA878 Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA878: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA878: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA878: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA878: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
- NICE TA900:Tixagevimab plus cilgavimab for preventing COVID-19
- NICE TA971: Remdesivir and tixagevimab plus cilgavimab for treating COVID-19
- NICE TA971: Remdesivir and tixagevimab plus cilgavimab for treating COVID-19
- Oseltamivir changed concentration and dosing dispenser of oral suspension: MHRA update Oct 2012
- Publication of an interim clinical commissioning policy: Remdesivir for patients hospitalised with COVID-19 (adults and children aged 12 years and older).
- UKMI Q&A: Can zanamivir be given to patients with renal impairment or patients on renal replacement therapies?
- UKMI Q+A :Can mothers breastfeed after taking oseltamivir and zanamivir
UKMI Q+A :Can oseltamivir be taken by patients taking methotrexate?- University Hospitals of Morecambe Bay: Antimicrobial guide secondary care
- West Lancashire Primary Care: Pan Mersey antimicrobial guide
- WHO: AWaRe classification of antibiotics for evaluation and monitoring of use, 2023