Lancashire and South Cumbria
Formulary
 
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5 Infections

 

Prescribers must follow the relevant local and national guidance when treating an infection. Some anti-infectives require approval from the local Trust microbiology team for use, consult local guidance for further information.

Not all anti-infectives listed in this chapter will be available in all localities; availability will be guided by local need and resistance patterns.

05-01-07 Linezolid

Linezolid
Formulary

Tablets 600mg

On advice of Microbiology only.

Severe optic neuropathy may occur rarely, particularly if linezolid is used for longer than 28 days.

Haematopoietic disorders (including thrombocytopenia, anaemia, leucopenia, and pancytopenia) have been reported in patients receiving linezolid. It is recommended that full blood counts are monitored weekly.

For the treatment of pneumonia or complicated skin and soft tissue infections on the recommendation of a microbiologist when used for up to 14-days
**Please refer to attached prescriber information sheet for more detail prior to prescribing**

Dosage and administration
Consultant microbiologists will request GPs to prescribe up to 14 days of treatment in the community ONLY.

If more than 14 days of treatment is required, either as an initial course or if an extension to the initial 14-day course is required, the patient must be referred back into secondary care.

The recommended dose of oral linezolid is 600 mg every 12 hours usually for 10–14 consecutive days (up to 28 days of treatment may be supplied by specialists).

Information for prescribers - to be read in conjunction with the SPC

Link  LSCMMG: Linezolid
Link  LSCMMG: Linezolid Prescriber Information Sheet

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Linezolid injection
Formulary

Intravenous infusion 600mg/300ml

On advice of Microbiology only.

Severe optic neuropathy may occur rarely, particularly if linezolid is used for longer than 28 days.

Haematopoietic disorders (including thrombocytopenia, anaemia, leucopenia, and pancytopenia) have been reported in patients receiving linezolid. It is recommended that full blood counts are monitored weekly.


Red View adult BNF  View SPC online  View childrens BNF