Lancashire and South Cumbria
Formulary
 
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6 Endocrine system
06-01-02-02 Biguanides

Metformin
Formulary

Tablets 500mg, 850mg

M/R tablets 500mg, 750mg, 1g

Only consider using modified release metformin if the patient cannot tolerate immediate release metformin.            

Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control

Reduction in the risk or delay of the onset of type 2 diabetes mellitus in adult, overweight patients with implied Glucose Tolerance and/or increased HbA1C who are at high risk for developing overt type 2 diabetes mellitus and still progressing towards type 2 diabetes mellitus despite implementation of intensive lifestyle change for 3-6 months.

Link  LSCMMG: Metformin
Link  MHRA Drug Safety Update June 2022: Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk
Link  NICE: Type 2 diabetes: prevention in people at high risk

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