Lancashire and South Cumbria
Formulary
 
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6 Endocrine system
06-05-02 Antidiuretic hormone antagonists

Demeclocycline
Formulary
150mg Capsules
 
For SIADH only (unlicensed indication if not secondary to malignant disease).

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Tolvaptan
Formulary

Tablets 7.5mg, 15mg, 30mg, 45mg, 60mg, 90mg

Autosomal dominant polycystic kidney disease (TA358) BlueTeq

Treatment of hyponatremia in adults, secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) (No Blueteq form required).

 Treatment of SIADH in patients requiring cancer chemotherapy is NHS England commissioned  

 Caution when prescribing - There is variation in the licensing of different products containing tolvaptan. Care should be taken to prescribe the correct product and dose for the indication.

 
Products are available containing a combination of tablet strengths, these are licensed for polycystic kidney disease only.
Link  LSCMMG: Tolvaptan
Link  NICE TA358 Tolvaptan for treating autosomal dominant polycystic kidney disease

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