Lancashire and South Cumbria
Formulary
 
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6 Endocrine system
06-01-01-02 Long Acting Insulin Analogues

Biosimilar Insulin Glargine
Formulary

3mL cartridge 100units/mL
3mL prefilled disposable Pen 100units/mL

First choice in new users


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Lantus® Insulin Glargine
Formulary

10mL vial
3mL cartridge for OptiPen® Pro 1
3mL prefilled disposable pen SoloSTAR®

Lantus® brand is not a preferred product in the LSCMMG antihyperglycaemics guideline. Biosimilars of Insulin glargine are also available for the treatment of NEW patients and patients assessed to need a medication change. Treatment should normally be started with the least expensive drug.


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Levemir® Insulin Detemir
Formulary
3mL cartridge for NovoPen®
3mL prefilled disposable FlexPen®

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Toujeo® Insulin glargine
Formulary

Pre-filled pen 300 units/mL

First line high strength long acting insulin (Toujeo Solostar)

Type 1 - in accordance with the recommendations in NICE NG17 and in those who experience an unacceptable frequency and/or severity of nocturnal hypoglycaemia on attempting to achieve better glycaemic control during treatment with first-line long-acting insulin analogues; or as a once daily insulin therapy for patients who require assistance with administering injections.

Type 2 - in accordance with the recommendations in NICE NG28 in those who suffer from symptomatic nocturnal hypoglycaemia whilst being treated with a first-line long-acting insulin analogue.

Link  LSCMMG: Insulin Toujeo® SoloStar® DoubleStar® Product Information Sheet & Good Practice Guide

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Tresiba® Insulin degludec
Formulary

100 units/ml 3ml cartridges
100units/ml pre-filled pens Flextouch
200units/ml pre-filled pens Flextouch

Must be commenced by a healthcare professional who is appropriately trained and experienced in the initiation of insulin
Specialists may exceptionally consider initiating insulin degludec if:
- Patient is experiencing poor glycaemic control or recurrent hypoglycaemic episodes with their existing long-acting insulin analogue or
- Patient is unable to take basal insulin at the same time each day

Second line high strength long-acting (Tresiba FlexTouch 200).
Third line long acting insulin analogue (Tresiba Flextouch 100).

Link  MHRA safety alert on availability of 2 strengths

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Xultophy® Insulin degludec and liraglutide
Formulary
Link  LSCMMG: Insulin degludec plus liraglutide

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