Lancashire and South Cumbria
Formulary
6 Endocrine system
06-01-02-03 Thiazolidinediones
Pioglitazone
Formulary
Tablets 15mg, 30mg, 45mg
MHRA: Insulin combined with pioglitazone: risk of cardiac failure
MHRA: Pioglitazone: risk of bladder cancer
Pioglitazone & Metformin
Formulary
Links
Diabetes UK: Diabetes when you’re unwell
LSCMMG: GLP-1 patient contract
LSCMMG: Guidelines for the Home Monitoring of Blood Glucose Levels
LSCMMG: Lancashire and South Cumbria ICB recommended meters, strips and devices Dec 2023
LSCMMG: Mounjaro® (Tirzepatide) for Type 2 Diabetes Position Statement
LSCMMG: Policy for Continuous Glucose Monitoring and Flash Glucose Monitoring to patients with Diabetes Mellitus
LSCMMG: Policy for the Provision of Insulin Pumps for Patients with Diabetes Mellitus
LSCMMG: Tirzepatide - Managing overweight and obesity
LSCMMG: Trans Female Gender Dysphoria Information Sheet
LSCMMG: Trans Male Gender Dysphoria Information Sheet
LSCMMG:Guideline for antihyperglycaemic therapy in adults with type 2 diabetes
MHRA Drug Safety Update April 2016: SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis
MHRA Drug Safety Update April 2016: SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis
MHRA Drug Safety Update April 2016: SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis
MHRA Drug Safety Update December 2021: Dapagliflozin (Forxiga): no longer authorised for treatment of type 1 diabetes mellitus
MHRA Drug Safety Update Feb 2019: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum)
MHRA Drug Safety Update Feb 2019: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum)
MHRA Drug Safety Update Feb 2019: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum)
MHRA Drug safety Update Feb 2019: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum)
MHRA Drug Safety update June 2015: SGLT2 inhibitors (canagliflozin, dapagliflozin, empagliflozin): risk of diabetic ketoacidosis
MHRA Drug Safety Update June 2019: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA Drug Safety Update June 2019: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA Drug Safety Update June 2019: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA Drug SAfety Update June2019: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA Drug Safety Update March 2020: SGLT2 inhibitors: monitor ketones in blood during treatment interruption for surgical procedures or acute serious medical illness
MHRA Drug Safety Update March 2020: SGLT2 inhibitors: monitor ketones in blood during treatment interruption for surgical procedures or acute serious medical illness
MHRA Drug Safety Update March 2020: SGLT2 inhibitors: monitor ketones in blood during treatment interruption for surgical procedures or acute serious medical illness
MHRA Drug Safety UpdateMarch 2020: SGLT2 inhibitors: monitor ketones in blood during treatment interruption for surgical procedures or acute serious medical illness
MHRA website
MHRA: Diabetes and driving
MHRA: Dipeptidylpeptidase-4 inhibitors: risk of acute pancreatitis
MHRA: Dipeptidylpeptidase-4 inhibitors: risk of acute pancreatitis
MHRA: Dipeptidylpeptidase-4 inhibitors: risk of acute pancreatitis
MHRA: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA: GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued
MHRA: Insulin combined with pioglitazone: risk of cardiac failure
MHRA: Ozempic▼(semaglutide) and Saxenda (liraglutide): vigilance required due to potentially harmful falsified products
MHRA: Ozempic▼(semaglutide) and Saxenda (liraglutide): vigilance required due to potentially harmful falsified products
MHRA: Pioglitazone: risk of bladder cancer
MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)
MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)
MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)
MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)
National Patient Safety Alert
NICE NG17: Type 1 diabetes in adults: diagnosis and management
NICE NG18: Diabetes (type 1 and type 2) in children and young people: diagnosis and management
NICE NG19: Diabetic foot problems: prevention and management
NICE NG28: Type 2 diabetes in adults: management
NICE NG28: Type 2 diabetes in adults: management
NICE NG3: Diabetes in pregnancy: management from preconception to the postnatal period
NICE TA288: Dapagliflozin in combination therapy for treating type 2 diabetes
NICE TA315: Canagliflozin in combination therapy for treating type 2 diabetes
NICE TA336: Empagliflozin in combination therapy for treating type 2 diabetes
NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
NICE TA418: Dapagliflozin in triple therapy for treating type 2 diabetes
NICE TA572: Ertugliflozin as monotherapy or with metformin for treating type 2 diabetes
NICE TA664: Liraglutide for managing overweight and obesity
NICE TA775: Dapagliflozin for treating chronic kidney disease
NICE TA875: Semaglutide for managing overweight and obesity
NICE TA924: Tirzepatide for treating type 2 diabetes
NICE TA942: Empagliflozin for treating chronic kidney disease
Risk of acute pancreatitis. MHRA safety update Sept 12
Serious hypersensitivity reactions & acute pancreatitis - Dear HCP Letter
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