Transdermal oestrogens are absorbed and should be used in the smallest effective amount and if required long term should be combined with an oral progestogen in women with an intact uterus. For low-dose vaginal oestrogen, a progesterone is not needed for endometrial protection, as systemic absorption of vaginal oestrogen is minimal.
Estradiol vaginal 10 microgram tablet |
Formulary
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Vaginal tablets 10microgram |
MHRA: Hormone replacement therapy (HRT): further information on the known increased risk of breast cancer with HRT and its persistence after stopping |
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Prasterone |
Formulary
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Vulvovaginal or vaginal atrophy in postmenopausal women having moderate to severe symptoms. |
LSCMMG: Prasterone |
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