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 Formulary Chapter 9: Nutrition and blood - Full Chapter
Notes:

This chapter of the formulary is under continual development, please let the team know if you have any comments about the contents: mlcsu.lscformulary@nhs.net

For more information about the formulary development process, please see: https://www.lancsmmg.nhs.uk/lancashire-and-south-cumbria-icb-formulary-development/

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09.06  Expand sub section  Vitamins
Paravit CF®
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Formulary
Amber 0
ICB

Paravit-CF is a ‘Food for Special Medical Purposes’ for the dietary management of patients with cystic fibrosis and is reimbursable on FP10.
Paravit CF Capsules contain:
• Vitamin A 1.5 mg (=5,000IU)
• Vitamin D3 37.5 µg (=1,500IU)
• Vitamin E 100 µg (=150IU)
• Vitamin K 5 mg
Paravit CF capsules provide an alternative vitamin supplementation option for Cystic Fibrosis patients, which offers patients a decreased oral medication load whilst also being a cost-effective option.
Paravit CF liquid is only available as an option for patients with swallowing difficulties or young children.

 
 
09.06.01  Expand sub section  Vitamin A
09.06.02  Expand sub section  Vitamin B group
Pyridoxine Hydrochloride
(Vitamin B6)
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Formulary
Amber 0

Tablets 10mg, 50mg

Green  in East Lancashire

 
 
Thiamine
(Vitamin B1)
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Formulary
Green
Tablets 50mg 
 
Thiamine (Pabrinex®)
(Vitamins B & C)
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Formulary
Red
High potency

Intravenous injection 10mL (2 amps)
Intramuscular injection 7mL (2 amps)

MHRA/CHM advice:serious allergic adverse reactions - see BNF 
Link  MHRA: Pabrinex: allergic reactions
 
09.06.02  Expand sub section  Oral vitamin B complex preparations
Vitamin B complex preparations (Vigranon B®)
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Formulary
Red

Not to be prescribed on TTO

Not for use in alcohol dependence

 
 
Vitamin B Tablets, Compound Strong
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Formulary
Red

For refeeding and Post Bariatric Surgery only

Refer to local policies

Not for use in alcohol dependence - thiamine may be used

 
Link  LSCMMG: Guidelines for the prescribing of nutritional supplements post bariatric surgery
 
09.06.02  Expand sub section  Other compounds to top
09.06.03  Expand sub section  Vitamin C
Ascorbic Acid
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Formulary
Green

Tablets 50mg, 100mg, 200mg & 500mg
Effervescent tablets 1g with zinc

Only to be used for prophylaxis and treatment of scurvy

 
 
09.06.04  Expand sub section  Vitamin D
Alfacalcidol (One-Alpha®)
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Formulary
Amber 0

Capsules 250 nanograms, 1 microgram
Oral drops 2 micrograms/mL (1 drop = 100 nanograms)

For severe renal impairment

Prescribers initiating treatment should indicate monitoring requirements.

 
Link  SPS - Alfacalcidol monitoring
 
Calcitriol (Rocaltrol®)
(1,25-dihydroxycolecalciferol)
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Formulary
Amber 0

Capsules 250 nanograms

 
 
Colecalciferol
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Formulary
Green

Follow local protocols

 
 
Colecalciferol 40000 unit  (Plenachol®)
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Formulary
Green
Capsules 40000 units

 
 
Colecalciferol and Calcium Carbonate
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Formulary
Green
 
 
Ergocalciferol (RPH Pharmaceuticals)
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Formulary
Amber 0

Injection 300,000 units

Consultant initiation only

Plastic syringes can be used 'off label' providing the injection is administered immediately after being drawn up into the syringe.

 
 
09.06.04  Expand sub section  Vitamin D with Calcium
09.06.05  Expand sub section  Vitamin E
Alpha Tocopheryl Acetate
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Formulary
Amber 0

Suspension 500mg/5mL

Other preparations may be available but are unlicensed - contact pharmacy for advice

 
 
09.06.06  Expand sub section  Vitamin K to top
Menadiol Sodium Phosphate
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Formulary
Green

Tablets 10mg

water soluble preparation for patients with fat malabsorption

 
 
Phytomenadione
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Formulary Injection 10mg/1mL (Konakion MM®) for IV injection only, not for IM injection.
Injection 2mg/0.2mL (Konakion MM Paediatric®)

Konakion MM Paediatric® may be administered by mouth, by IM injection or by IV injection - see UHMB guideline for administration of vitamin k to neonates 
 
09.06.07  Expand sub section  Multivitamin preparations
Multivitamin preparations (Abidec®)
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Formulary
Green
Vitamins A, B group, C and D

Oral drops 
 
Multivitamin preparations (Dalivit®)
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Formulary
Green
Vitamins A, B group, C and D

Oral drops 
 
Mutivitamin
(Vitamins BPC capsules)
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Formulary
Green
 
Link  LSCMMG: Over the Counter Items that Should not be Routinely Prescribed in Primary Care Policy
 
Renavit®
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Formulary
Green

Dietary management of water-soluble vitamin deficiency in adults with renal failure on dialysis
For G.P prescribing

 
 
09.06.07  Expand sub section  Vitamin and mineral supplements and adjuncts to synthetic diets
Vitamin and mineral supplements (Forceval, & Forceval Soluble®)
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Formulary
Green

Tablets

On dieticians request only for patients with swallowing difficulties or enteral feeding tubes

Amber 0 Post-surgery if gastric bypass

For use post bariatric surgery please consult link below

 
Link  LSCMMG: Guidelines for the prescribing of nutritional supplements post bariatric surgery
 
Vitamin and mineral supplements (Ketovite®)
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Formulary
Green
Tablets
Liquid 
 
 ....
 Non Formulary Items
  
Key
Restricted Drug Restricted Drug
Unlicensed Drug Unlicensed
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
ICB
ICB
Green Low Carbon

Low carbon footprint

Amber Medium Carbon

Medium carbon footprint

Red High carbon footprint

High carbon footprint

Status Description

Green

Green: Appropriate for initiation and ongoing prescribing in both primary and secondary care. Generally, little or no routine drug monitoring is required.  

Green Restricted

Green (Restricted): Appropriate for initiation and ongoing prescribing in both primary and secondary care provided: Additional criteria specific to the medicine or device are met, or The medicine or device is used following the failure of other therapies as defined by the relevant LSCMMG pathway. Generally, little or no routine drug monitoring is required.   

Red

Red medicines: Medicine is supplied by the hospital for the duration of the treatment course. Primary care initiation or continuation of treatment is not recommended unless exceptional circumstances such as specialist GP. Red medicines are those where primary care prescribing is not recommended. These treatments should be initiated by specialists only and prescribing retained within secondary care. They require specialist knowledge, intensive monitoring, specific dose adjustments or further evaluation in use. If however, a primary care prescriber has particular specialist knowledge or experience of prescribing a particular drug for a particular patient it would not always be appropriate for them to expect to transfer that prescribing responsibility back to secondary care. There should be a specific reason and a specific risk agreement, protocol and service set up to support this. Primary care prescribers may prescribe RED medicines in exceptional circumstances to patients to ensure continuity of supply while arrangements are made to obtain ongoing supplies from secondary care.  

Amber 0

Amber level 0: Suitable for prescribing in primary care following recommendation or initiation by a specialist. Little or no specific monitoring required. Patient may need a regular review, but this would not exceed that required for other medicines routinely prescribed in primary care. Brief prescribing document or information sheet may be required. Primary care prescribers must be familiar with the drug to take on prescribing responsibility or must get the required information. When recommending or handing over care, specialists should ask primary care prescribers to take over prescribing responsibility, and should give enough information about the indication, dose, monitoring requirements, use outside product licence and any necessary dose adjustments to allow them to confidently prescribe.  

Amber 1

Amber level 1 (with shared care): Suitable for prescribing in primary care following recommendation or initiation by a specialist. Minimal monitoring required. Patient may need a regular review, but this would not exceed that required for other medicines routinely prescribed in primary care. Full prior agreement about patient’s on-going care must be reached under the shared care agreement. Primary care prescribers are advised not to take on prescribing of these medicines unless they have been adequately informed by letter of their responsibilities with regards monitoring, side effects and interactions and are happy to take on the prescribing responsibility. A copy of locally approved shared care guidelines should accompany this letter which outlines these responsibilities. Primary care prescribers should then tell secondary care of their intentions as soon as possible by letter so that arrangements can be made for the transfer of care.  

Amber 2

Amber level 2 (with shared care and enhanced service): Initiated by specialist and transferred to primary care following a successful initiation period. Significant monitoring required on an on-going basis. Full prior agreement about patient’s on-going care must be reached under the shared care agreement. Suitable for enhanced service. These medicines are considered suitable for GP prescribing following specialist initiation of therapy, as per shared care document which will be sent out with the request to prescribe, with on-going communication between the primary care prescriber and specialist. Amber Level 2 medicines require significant monitoring for which an enhanced service may be suitable. (Subject to local commissioning agreements).  

Do Not Prescribe

Do not prescribe: NOT recommended for use by the NHS in Lancashire and South Cumbria. Includes medicines that NICE has not recommended for use and terminated technology appraisals, unless there is a local need.  

Grey

Grey medicines: Medicines which have not yet been reviewed or are under the review process. GPs and specialists are recommended not to prescribe these drugs. This category includes drugs where funding has not yet been agreed.   

Multiple

Refer to local guidance.  

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